October Newsletter

Join us for our free and informative webinar workshop!

We’re very excited to showcase our animal free and biocompatible PeptiGels® and PeptiInks® in partnership with our UK distributor, Appleton Woods, who boasts a comprehensive range of quality laboratory equipment, consumables and reagents.

Together we will highlight the key advantages of 3D cell culture for applications within regenerative medicine, tissue engineering, cell biology, and drug discovery.

This online workshop webinar will also include live demonstrations by our senior scientist, Dammy, who has a wealth of expertise within 3D cell culture, along with a live Q&A session. You don’t want to miss out on this remarkable opportunity – registering for free will enter you into our prize draw to win a PeptiGel® trial pack worth over £400.

Click here to secure your place

Using computational fluid dynamics to simulate PeptiInks® extrusion

It is widely established that Covid-19 has had an unprecedented impact on scientific research. For almost all there has been a dramatic shift in the way we are approaching our work. This has not only involved a transition to virtual meetings, conferences and online communication, but for many PhD students it has also involved a shift in project emphasis. In particular lockdown has seen a rise in review papers being written, results analysed leading to papers published and often the transition to added computational analysis.

We decided to look at what one of our CASE-award PhD students, Patricia Santos, has been doing during the lockdown. Patricia is based at University College London (UCL) under the supervision of Dr. Deepak Kalaskar and her work is focussed on 3D bioprinting tissues using
animal-free peptide-based bioinks; PeptiInks®. She started her research by trying to understand the forces that arise during the printing process in an extrusion-based 3D bioprinter. These forces are vital factors responsible for regulating cell survival during cell-laden bioprinting process.

We recently interviewed her on her lockdown work experience, and this is what she said…
“Using computational fluid dynamics, I have developed with the use of ANSYS Fluent software, a model by which the extrusion of different materials such as PeptiInks® can be simulated using various printing head sizes and extrusion pressures. The materials extruded are characterised by rheology and the printing head sizes and pressures can be changed to model different scenarios. The aim of the simulations is to find the optimal parameter combination that produces the lowest shear stress forces, maximising cell survivability”

Further information on this work will be presented at the 6th Annual Surgery Virtual Meeting, 5th – 9th October, 2020. Further details of the programme can be found here. To learn more about Manchester BIOGEL’s PeptiInks® and our collaborative opportunities, please get in touch.

3DBioNet’s Virtual Workshop hosted by Prof. Aline Miller

Manchester BIOGEL’s CEO, Aline Miller, recently hosted one of the Technology-Touching Lives (TTL)’s initiatives – 3DBioNet’s virtual workshop that took place on the 14th and 15th of September 2020. The virtual meeting hosted over 90 scientists from academia, industry and various funding bodies to discuss the latest discoveries and current innovative ways to advance the field of 3D cell culture models.

The meeting had two keynote lectures given by Prof. Felicity Rose (University of Nottingham) describing the use of biomaterials to influence cell phenotype and behavior, and Dr. Chiara Braconi (University of Glasgow) describing the use of patients derived organoids as a novel tool to model biliary cancers and implement personalized therapy.

There were several other interesting and interactive sessions including session talks, flash posters, industry highlight presentations and the impact of social media for scientists. In particular, it was interesting to see how our peptide-based hydrogels – PeptiGels® – have enhanced several innovative projects. Some examples include the industry highlight presentation given by Dr. Natasha Lewis from Cell Guidance Systems that highlighted the use of PeptiGels® with their PODS systems to enhance 3D cell culture, the flash poster presentation given by Dr. Priyanka Gupta that showed the use of PeptiGels® in the development and characterisation of a 3D model of epithelial ovarian cancer towards therapeutic assessment, and also a session talk by our very own Senior Scientist, Dr. Dammy Olayanju that highlighted the use of PeptiGels® for the growth and culture of physiologically-relevant organoids for pharmacological and toxicological studies and personalized medicine.

Get in touch

For more information about our technology, our products or how we can support your research please get in touch: