Our peptide materials are fully synthetic and spontaneously self-assemble to form 3D nano-fibrous hydrogels that mimic the native extracellular matrix (ECM). The mechanical stiffness of these hydrogels is easily varied and can match the stiffness of any tissue type. The fibre surfaces can be (bio) chemically functionalised with several biomimetic peptide sequences from key ECM proteins that are proven to signal and enhance biological processes. These include RGD (fibronectin), IKVAV (laminin), YIGSR (laminin) and GFOGER (collagen).
The ability to tune the properties of the peptide hydrogels to provide the optimal environment for your cells’ needs, makes them the ideal synthetic alternative to animal derived matrices such as MatrigelTM and collagen.