About Biogel Team

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So far Biogel Team has created 15 blog entries.

Publication: Engineering a Cell-Hydrogel-Fibre Composite to Mimic the Structure and Function of the Tendon Synovial Sheath

2021-07-28T11:10:23+01:00July 26th, 2021|

A study by Dr. Angela Imere and her group at the University of Manchester highlighted the support of PeptiGel® Alpha4 in the development of a bilayer membrane to act as anti-adhesion system, aiding restoration of tendon function. This shows that our fully-defined peptide-based hydrogels can support good lubrication properties, 3-dimensional (3D) growth and maintenance of rabbit synoviocytes evidenced with the production of specific matrix components such as hyaluronic acid.

Publication: Neutrally Charged Self-assembling Peptide Hydrogel Recapitulates in vitro Mechanisms of Breast Cancer Progression

2021-07-12T14:43:01+01:00July 12th, 2021|

Dr. Clough's paper highlights how PeptiGel® can be used to successfully mimic the 3D tumour microenvironment of breast cancer in vitro. PeptiGel® Alpha 1 was able to closely mimic the mechanical properties of breast tumour tissue and supported the viability and growth of breast cancer cell lines MCF-7 and MDA-MB-231 for 14 days. In addition to this, key features of solid tumors such as hypoxia and invasion were recapitulated.

Publication: Self-Assembling Polypeptide Hydrogels as a Platform to Recapitulate the Tumor Microenvironment

2021-07-12T14:38:13+01:00July 12th, 2021|

Dr Armando Del Rio Hernandez’s research group (Imperial College London) used PeptiGels® to mimic the mechanical and chemical environment of both healthy and cancer tissue. Results showed the tumour mimicking PeptiGel® (stiff and acidic) to induce a biomechanical response in PDAC suit-2 cells, resulting in an increased proliferation (expression of Ki67).

Job Vacancy: Business Development Executive

2021-07-12T13:48:10+01:00May 19th, 2021|

Manchester BIOGEL is seeking an ambitious and highly driven individual who is eager to develop their career in business development and sales and become an integral part of a fast-growing and dynamic company based in Alderley Park, Cheshire. This is an excellent opportunity for someone holding a scientific degree with experience of working in a sales role within a biotech, life sciences or pharmaceutical organisation or similar.

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